NAD / MOTS-c / 5-Amino-1MQ Peptide Blend Description The BioLongevity Labs NAD /MOTS-c/5-Amino-1MQ Blend unites three distinct compounds that converge on cellular energy, mitochondrial function, and metabolic regulation: NAD (100 mg) replenishes the central redox cofactor required for metabolism, DNA repair, and sirtuin activation [1][2][3]. MOTS-c (10 mg) is a mitochondria-derived peptide that activates AMPK, regulates nuclear gene expression under metabolic stress, and enhances insulin sensitivity [4][5][6]. 5-Amino-1MQ (10 mg) inhibits NNMT, raising NAD levels while modulating histone methylation and fat metabolism pathways [7][8][9]. Together, their mechanisms are designed to: Enhance mitochondrial and cellular energy balance by restoring NAD pools and activating AMPK [1][4][7]. Improve metabolic health by reducing adiposity, sustaining muscle function, and optimizing glucose regulation [2][5][8]. Support cognitive and longevity research through effects on neuroinflammation, oxidative stress, and cellular senescence [3][6][9]. Peptide Structures NAD (Nicotinamide Adenine Dinucleotide) Molecular Formula: C₂₁H₂₇N₇O₁₄P₂ Molecular Weight: 663.43 g/mol PubChem CID: 925 CAS Number: 53-84-9 Synonyms: β-Nicotinamide adenine dinucleotide, DPN, Coenzyme I, Diphosphopyridine nucleotide MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg Molecular Formula: C₁₀₁H₁₅₂N₂₈O₂₂S₂ Molecular Weight: 2174.6 g/mol PubChem SID: 255386757 CAS Number: 1627580-64-6 Synonyms: Human MOTS-c, UNII-A5CV6JFB78, MOTS-c trifluoroacetate salt 5-Amino-1MQ (5-Amino-1-methylquinolinium) Molecular Formula: C₁₀H₁₁N₂ Molecular Weight: 159.21 g/mol PubChem CID: 950107 CAS Number: — Synonyms: 5-amino-1-methylquinolinium, SCHEMBL6403148, CHEMBL4116828, ZMJBCEIHNOWCMC-UHFFFAOYSA-O, STL196667 This synergistic triad provides a unique investigational platform for metabolism, neuroprotection, and healthy aging research. Blend Structure Ingredient Dose (per capsule) Key Actions NAD 100 mg Cofactor in redox metabolism; activates sirtuins & AMPK; supports DNA repair & mitochondrial biogenesis [1][2][3] MOTS-c 10 mg Mitochondria-encoded peptide; AMPK activation; improves insulin sensitivity; prevents metabolic dysfunction [4][5][6] 5-Amino-1MQ 10 mg NNMT inhibitor; ↑NAD ; ↓adiposity; epigenetic modulation; metabolic & oncology research [7][8][9] Research Areas Cellular Energy & Mitochondrial Function Metabolic Regulation & Obesity Research Muscle Preservation & Physical Performance Neuroprotection & Cognitive Function Longevity & Anti-Aging Mechanisms Preclinical Cancer Research
